Publications

Selected Publications of the Last 5 Years

Popa A, Genger JW, Nicholson M, Penz T, Schmid D, Aberle SW, Agerer B, Lercher A, Endler L, Colaço H, Smyth M, Schuster M, Grau M, Martinez F, Pich O, Borena W, Pawelka E, Keszei Z, Senekowitsch M, Laine J, Aberle JH, Redlberger-Fritz M, Karolyi M, Zoufaly A, Maritschnik S, Borkovec M, Hufnagl P, Nairz M, Weiss G, Wolfinger MT, von Laer D, Superti-Furga G, Lopez-Bigas N, Puchhammer-Stöckl E, Allerberger F, Michor F, Bock C, Bergthaler A. Mutational dynamics and transmission properties of SARS-CoV-2 superspreading events in Austria. Science Translational Medicine. 2020. PMID: 33229462.

Lercher A, Bhattacharya A, Popa AM, Caldera M, Schlapansky MF, Baazim H, Agerer B, Gürtl B, Kosack L, Májek P, Brunner JS, Vitko D, Pinter T, Genger JW, Orlova A, Pikor N, Reil D, Ozsvár-Kozma M, Kalinke U, Ludewig B, Moriggl R, Bennett KL, Menche J, Cheng PN, Schabbauer G, Trauner T, Klavins K, Bergthaler A. Type I interferon signaling disrupts the hepatic urea cycle and alters systemic metabolism to suppress T cell function. Immunity. 2019 Nov 26. pii: S1074-7613(19)30458-3. PMID: 31784108.

Baazim H, Schweiger M, Moschinger M, Xu H, Scherer T, Popa A, Gallage S, Ali A, Khamina K, Kosack L, Vilagos B, Smyth M, Lercher A, Friske J, Merkler D, Aderem A, Helbich TH, Heikenwälder M, Lang PA, Zechner R and Bergthaler A. CD8(+) T cells induce cachexia during chronic viral infection. Nature Immunology. 2019 Jun;20(6):701-710. PMID: 31110314.

Lercher A, Baazim A, Bergthaler A. Systemic immunometabolism: challenges and opportunities. Immunity. 2020 Sept 15. https://doi.org/ 10.1016/j.immuni.2020.08.012.

Krausgruber T, Fortelny N, Fife-Gernedl V, Senekowitsch M, Schuster LC, Lercher A, Nemc A, Schmidt C, Rendeiro F, Bergthaler A, Bock C. Structural cells are key regulators of organ-specific immune responses. Nature 2020 Jul;583(7815):296-302. PMID: 32612232.

Bhattacharya A, Hegazy AN, Deigendesch N, Kosack L, Cupovic J, Kandasamy RK, Hildebrandt A, Merkler D, Kühl AA, Schliehe C, Panse I, Vilagos B, Khamina K, Arnold I, Flatz L, Xu HC, Lang PA, Aderem A, Superti-Furga G, Colinge J, Ludewig B, Löhning M*, Bergthaler A*. Superoxide dismutase 1 protects hepatocytes from type I interferon-driven oxidative damage. Immunity. 2015 Nov 17;43(5):974-86. PMID: 26588782.

Schliehe C, Flynn EK, Vilagos B, Richson U, Swaminathan S, Bosnjak B, Bauer L, Kandasamy RK, Griesshammer IM, Kosack L, Schmitz F, Litvak V, Sissons J, Lercher A, Bhattacharya A, Khamina K, Trivett AL, Tessarollo L, Mesteri I, Hladik A, Merkler D, Kubicek S, Knapp S, Epstein MM, Symer DE, Aderem A, Bergthaler A. The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection. Nature Immunology. 2015 Jan;16(1):67-74. PMID: 25419628.

Lercher A, Popa AM, Viczenczova C, Kosack LJ, Klavins K, Agerer B, Opitz CA, Lanz TV, Platten M, Bergthaler A. Type I interferon reprograms hepatocyte metabolism and reveals novel compensatory mechanism of the tryptophan-kynurenine pathway in viral hepatitis. PLoS Pathogens. 2020 Oct 12;16(10):e1008973. PMID: 33045014

Kosack L, Wingelhofer B, Popa A, Orlova A, Agerer B, Vilagos B, Majek P, Parapatics K, Lercher A, Ringler A, Klughammer J, Smyth M, Khamina K, Baazim H, de Araujo ED, Rosa DA, Park J, Tin G, Ahmar S, Gunning PT, Bock C, Siddle HV,Woods GM, Kubicek S, Murchison EP, Bennett KL, Moriggl R*, Bergthaler A*. ERBB-STAT3 axis drives Tasmanian devil facial tumor disease. Cancer Cell. 2019 Jan 14;35(1):125-139.e9. PMID: 30645971.

 

 

 

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All Publications

Complete list of publications

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